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PKM2 plays key roles in reprogramming cancer cells from energy production to growth (Warburg Effect). The dimeric form of the enzyme is not only less active in glycolysis but can also move into the nucleus to promote the transcription of other cancer-causing genes. A substrate analogon (red) is bound to the active site. PKM2 is a target for anti-cancer therapies. PDB entry: 6WP3.

A ball-and-stick molecular model of the hormone Orexin, also known as Hypocretin. Orexin is involved in the regulation of the sleep/wake cycle and it stimulates apetite, wakefulness and energy expenditure. It has been linked with Alzheimer's disease. Isolated on white.

3D cartoon and Gaussian surface models. PDB 2aai, white background.

Abstract geometric shape

Indoleamine 2,3 dioxygenase 1 (IDO1) protein. Tryptophan catabolic enzyme of the kynurenine pathway. 3D illustration.

DNA A-T Pair

Cytochrome P450 molecule. CYP 3A4 is the most promiscuous of the human CYP enzymes. Molecular model. 3D rendering. Illustration

Rendered coronavirus/2019-nCoV single-stranded RNA, built from experimentally determined Ebola virus crystal structure. Color symbols - bluewhite=carbon, pink=oxygen, lightblue=nitrogen, white=hydrogen, lavender=phosphorus

Avibactam is a diazobicyclooctane inhibitor of gram-negative and gram-positive bacteria. Avibactam (red) inhibits the bacterial enzyme beta-lactamase (blue) of Clostridioides difficile.

A ball and stick + ribbons model of HIV protease - an enzyme that is the target of much AIDS and HIV research.

3D cartoon and Gaussian surface models, chain id color scheme, PDB 4ci9, white background

Abstract geometric shape

Glucose-6-phosphate dehydrogenase (G6PD) protein. Enzyme of the pentose phosphate pathway that generates co-enzyme NADPH. 3D illustration.

Tryptophan or Trp is an alpha-amino acid that is used in the biosynthesis of proteins, 3d illustration

Colorful Molecules Background

PETase (left) degrades polyethylene terephtalate (PET) into monohydroxyethyl terephthalate (MHET) and MHETase degrades MHET ethylene glycol (EG) and terephthalic acid (TPA). The substrates in the binding sites are depicted in red.

A ball and stick model of Ethyl Eicosapentaenoic Acid or E-EPA. It is an omega-3 polyunsaturated fatty acid.

3D cartoon and Gaussian surface models, PDB 1j7n, chain id color scheme, white background

Rendered Remdesivir molecule in 3D, an experimental drug from Gilead, used to cure the first case of 2019-nCoV in the United States (for a patient at Seattle, Washington). The model showed accurate atom connection and stereochemistry, which was professionally checked. Color symbols - light blue=carbon, red=oxygen, blue=nitrogen, white=hydrogen, green=phosphorus

Botulinum toxin neurotoxic protein, 3D rendering. Produced by Clostridium botulinum. Cosmetically used to treat wrinkles.

Amino Acid Lysine

Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration

3d structure of l-glucose molecule.

Cholera toxin, molecular model. Cholera toxin (choleragen) is a protein complex secreted by the bacterium Vibrio cholerae, that causes the disease cholera. It is made up of a wedge-shaped A subunit (right part of illustration) and five B subunits (left part of illustration) that form a ring which binds to the intestinal lining. In its most severe forms, cholera is one of the most rapidly fatal illnesses known.

A ball and stick model of a molecule of Human Glucagon, a hormone produced in the pancreas and used by the body to raise levels of glucose in the blood. Glucagon worksin the opposite manner to Insulin, which lowers levels of glucose in the blood - together they work to keep glucose levels stable.

3D cartoon and Gaussian surface models, PDB 3hg3, white background

Rendered Remdesivir molecule in 3D, an experimental drug from Gilead, used to cure the first case of 2019-nCoV in the United States (for a patient at Seattle, Washington). The model showed accurate atom connection and stereochemistry, based on the chemical structure available in public space from U.S. National Library of Medicine, which was professionally checked. Color symbols - green=carbon, red=oxygen, blue=nitrogen, white=hydrogen, purple=phosphorus

Taq polymerase (Thermus aquaticus polymerase) enzyme bound to DNA, 3D rendering. Protein used in PCR (polymerase chain reaction).

Molecular model of Adenosine triphosphate, or Adenosine-5'-triphosphate (ATP)

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