Keywords: No2toxpathwaysEPA.png en Pathways through which NO2 causes damage in humans Original caption Note Pathways indicated by a dotted line are those for which evidence is limited to findings from experimental animal studies while evidence from controlled human exposure studies is available for pathways indicated by a solid line Dashed lines indicate proposed links to the outcomes of asthma exacerbation and respiratory tract infections Key events are subclinical effects endpoints are effects that are generally measured in the clinic and outcomes are health effects at the organism level NO2 nitrogen dioxide; ELF epithelial lining fluid 2016-01-28 U S EPA Integrated Science Assessment for Oxides of Nitrogen “ Health Criteria 2016 Final Report U S Environmental Protection Agency Washington DC EPA/600/R-15/068 2016 Page 4-62 See https //cfpub epa gov/ncea/isa/recordisplay cfm deid 310879 National Center for Environmental Assessment-RTP Division Office of Research and Development U S Environmental Protection Agency Research Triangle Park NC other versions PD-USGov Ecotoxicology |